California ». San Diego. $57. Flights to San Diego, San Diego. Find flights to San Diego from $25. Fly from San Francisco Bay Area on Frontier, Spirit Airlines and more. Search for San Diego flights on KAYAK now to find the best deal. San Francisco to San Diego Flights. Flights from SFO to SAN are operated 87 times a week, with an average of 12 flights per day. Departure times vary between 05:40 - 22:15. The earliest flight departs at 05:40, the last flight departs at 22:15. However, this depends on the date you are flying so please check with the full flight schedule above ...San Francisco to San Diego road trip is one of the best journeys you can experience in the USA.The 502 miles of San Francisco to San Diego drive takes around 7 hours and 45 mins without stops.. This article includes 14 tips that turn your San Francisco to San Diego drive into an unforgettable journey. So if you’re looking for the best hotels, …Flights between San Diego, CA and San Francisco, CA starting at CA$32. Choose between Alaska Airlines, Frontier Airlines, or United Airlines to find the best price. …The average bus between San Francisco and Lucky Seafood - San Diego, CA takes 16h 32m and the fastest bus takes 13h 40m. There is at least one bus per day from San Francisco to Lucky Seafood - San Diego, CA. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.Finish your trip in San Diego for two nights! ... San Antonio, TX San Francisco, CA Seattle, WA Washington, DC Search by Map View Top 10 Destinations View all Destinations. Flash Sale 15+ Nights. Save $600. For a limited time only, save $600 per couple on rail vacations inclusive of 15 nights or more!Traveling by bus from San Francisco to San Diego usually takes around 15 hours and 14 minutes, but the fastest FlixBus US bus can make the trip in 10 hours and 35 minutes. …Delta and United Airlines fly from Los Angeles Airport (LAX) to San Diego every 4 hours. Alternatively, LAX LINQ operates a bus from LAX Terminal 3 Lower Level pickup to 2728 Congress Street, San Diego Old Town twice daily. Tickets cost $55 - $75 and the journey takes 3h. Airlines.Jul 29, 2018 · For the most current highway updates, go to the CalTrans website and enter the highway number (Highway 1) in the search bar, or call 1.800.427.7623 before you hit the road. Also, make sure you have a good Pacific Coast Highway map, whether it is on your phone, or on good ol’ fashioned paper! READ MORE: San Francisco - San Francisco, CA. 2nd Cheapest. San Diego - Santa Fe Depot. $65. 2nd Cheapest. 10:00 PM. 10 h 35 m. 8:35 AM. San Francisco - 409 Townsend St, SF. ... Once in San Diego, you can start exploring the city and discover its surroundings. The top sights and things to do are Botanical Building and Lily Pond, Coronado, SeaWorld San ...Line 992 bus • 12 min. Take the line 992 bus from Broadway & Kettner Bl to San Diego Int'l Airport & Terminal 1 992. $2 - $5. Economy. 09/26/24 - 09/30/24. from. $ 159*. Viewed: 19 hours ago. From. San Diego (SAN) To. San Francisco (SFO) I regularly fly to San Diego to visit family and the key is planning ahead. From my experience, southwest and Alaska are the cheapest - it’s worth creating an account with the airlines to get emails when they’re having sales. Southwest regularly runs deals from SF to SD for $49 (one way) - they actually just had one that ended yesterday.The most magnificent Diego Rivera mural in San Francisco is the piece entitled the Pan American Unity. This enormous work of art stands 22 feet tall and is 75 feet wide. It is made up of 10 panels and is the largest significant piece of work he did. It is also the last official fresco he created in the US.Onboard services are subject to availability. Low-cost bus route from San Francisco, CA to San Diego, CA and from San Diego, CA to San Francisco, CA Secure online payment Free Wi-Fi and plug sockets on board 2 pieces of free luggage 2,500+ destinations in Canada, US and Europe starting from $4.99!Visit the best ports in the Mexican Riviera and get a taste of the warm sun, diverse culture and festive flavors of the region. Each itinerary offers something unique, like more time ashore in Cabo or the unparalleled ports of La Paz or Loreto on our 10-day cruises to Mexico. Up to 35% off + 3rd & 4th Guests Sail Free †. The route takes you through Santa Cruz, Monterey, Big Sur, San Simeone, San Luis Obispo, Santa Barbra, Santa Monica, Venice Beach, Huntington Beach, Laguna Beach and finally to San Diego. I recommend that for Day 1 on the road you aim to get from San Francisco to Monterey where you will stay over night. You will spend the day in Santa Cruz and ... The official way to drive Route One is to stay on it (or the Historic 101) from San Francisco to San Diego BUT after you get off the Golden Gate Bridge, the Pacific Coast Highway is a four-lane road which gets snarled up with traffic. It’s not exactly the way you’ll want to start the drive of a lifetime, so we jumped off and headed towards ...There are 4 airlines that fly nonstop from San Francisco to San Diego. They are: Alaska Airlines, Frontier, Southwest and United Airlines. The cheapest price of all airlines flying …San Francisco - San Francisco, CA. 2nd Cheapest. San Diego - Santa Fe Depot. $65. 2nd Cheapest. 10:00 PM. 10 h 35 m. 8:35 AM. San Francisco - 409 Townsend St, SF. ... Once in San Diego, you can start exploring the city and discover its surroundings. The top sights and things to do are Botanical Building and Lily Pond, Coronado, SeaWorld San ...There is no avoiding Los Angeles when driving from SF to SD. Even the coast is LA itself, from just south of Ventura all the way to the South Bay -- that coast is LA. SF to SD is at least a 9 hour drive. Report inappropriate content. BonnieandClyde86.stay for about 1.5 hours. and leave at 7:02 pm. drive for about 23 minutes. 7:25 pm arrive in San Francisco. eat at Ike's Place. stay at Top of the Mark. day 2 driving ≈ 6 hours. find more stops. The system will run from San Francisco to the Los Angeles basin in under three hours at speeds capable of over 200 miles per hour. The system will eventually extend to Sacramento and San Diego, totaling 800 miles with up to 24 stations. There is no direct train from San Diego to San Francisco, but it is still very easy to get into the city. Take the Amtrak Pacific Surfliner north to Oakland, which is very close to San Francisco. From Oakland, simply take the Red or Yellow BARTA line, which only takes about 12 minutes and costs just $4. Overall, the trip takes roughly 12 hours.Cheap Flights from Seattle to San Diego (SEA-SAN) Prices were available within the past 7 days and start at $50 for one-way flights and $100 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. Book one-way or return flights from Seattle to San Diego with no change fee on selected ...Direct. Wed, Jun 12 SAN – SFO with Frontier Airlines. Direct. from $52. San Diego.$56 per passenger.Departing Wed, Jun 26, returning Tue, Jul 2.Round-trip flight with Frontier Airlines.Outbound direct flight with Frontier Airlines departing from San Francisco International on Wed, Jun 26, arriving in San Diego International.Inbound direct ... San Francisco. SAN. San Diego. $66. Roundtrip. found 4 hours ago. Book one-way or return flights from San Francisco to San Diego with no change fee on selected flights. Earn your airline miles on top of our rewards! Get great 2024 flight deals from San Francisco to San Diego now! Jun 16, 2021 · San Diego and San Francisco, two of California's most popular coastal cities, are about 500 miles (806 kilometers) apart. You can make the trip by almost any common form of transportation, including train, bus, car, or plane. The fastest—and usually most affordable—way to get from San Diego to San Francisco is by flying. Find company research, competitor information, contact details & financial data for SF SAN DIEGO INC. of San Diego, CA. Get the latest business insights from Dun & Bradstreet.Use Google Flights to find cheap departing flights to San Diego and to track prices for specific travel dates for your next getaway. The trip from San Francisco to San Diego takes as short as 10 hours 35 minutes and could cost as little as $47.99 . The first bus departs at 6:00 am and the last bus departs at 11:30 pm . Greyhound operates 8 bus rides daily between San Francisco and San Diego. When traveling with Greyhound to San Diego from San Francisco, expect free Wifi ... Line 992 bus • 12 min. Take the line 992 bus from Broadway & Kettner Bl to San Diego Int'l Airport & Terminal 1 992. $2 - $5.Overview: Train from San Francisco, CA to San Diego, CA. Trains from San Francisco, CA to San Diego, CA cover the 457 miles (737 km) long trip taking on average 12 h 45 min with our travel partners like Amtrak. You can get the cheapest train tickets for this route for as low as $83 (€73), but the average price of train tickets is $93 (€82).Economy. 09/26/24 - 09/30/24. from. $ 159*. Viewed: 19 hours ago. From. San Diego (SAN) To. San Francisco (SFO)The total driving distance from San Francisco, CA to San Diego, CA is 501 miles or 806 kilometers. Your trip begins in San Francisco, California. It ends in San Diego, California. If you are planning a road trip, you might also want to calculate the total driving time from San Francisco, CA to San Diego, CA so you can see when you'll arrive at ...The best things to do in San Diego, California, include exploring Balboa Park, eating authentic Mexican food in Old Town, and relaxing on the shores of La Jolla.SD to SF road trip - San Diego Forum. United States ; California (CA) San Diego ; San Diego Travel Forum; Search. Browse all 31,458 San Diego topics » ... Where can I get …City Bus. City Bus Public transit is available to and from the Airport and downtown San Diego on the Metropolitan Transit System's Route 992, which stops at Terminals 1 and 2, and operates between 5:00 a.m. and midnight, every 15 minutes on weekdays and every 30 minutes on weekends and holidays.. This frequent bus service connects with Trolley, …The total driving distance from San Francisco, CA to San Diego, CA is 502 miles or 808 kilometers. Each person would then have to drive about 251 miles to meet in the middle. It will take about 4 hours and 3 minutes for each driver to arrive at the meeting point. For a flight, the straight line geographic midpoint coordinates are 35° 16' 25" N ... San Francisco. San Diego. The average train between San Francisco and San Diego takes 16h 30m and the fastest train takes 16h 27m. The train runs, on average, 6 times per week from San Francisco to San Diego. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date. See more reviews for this business. Top 10 Best Sf Supermarket in San Diego, CA - April 2024 - Yelp - SF Supermarket, 99 Ranch Market, Nijiya Market - San Diego, Mitsuwa Marketplace, Balboa International Market, Tokyo Central & Main - San Diego, H Mart - San Diego, Ocean Beach People's Food Co-op, Lucky Seafood.Find flights to San Diego from C$ 54. Fly from San Francisco on Frontier, Delta, Alaska Airlines and more. Search for San Diego flights on KAYAK now to find the best deal. stay for about 1.5 hours. and leave at 7:02 pm. drive for about 23 minutes. 7:25 pm arrive in San Francisco. eat at Ike's Place. stay at Top of the Mark. day 2 driving ≈ 6 hours. find more stops. Cheap Flights from San Diego to San Francisco (SAN-SFO) Prices were available within the past 7 days and start at $29 for one-way flights and $53 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. Book one-way or return flights from San Diego to San Francisco with no change fee on ... San Diego to San Francisco Road Trip Distance: approximately 600 miles Best Car for this road trip: Convertible. Start Your Trip. 1. San Diego. San Diego Skyline. San Diego is a gorgeous city filled with a vast array of entertainment options. Before you leave town, spend a little time exploring the beaches and Balboa Park, home of the world ...SF 4 SD 5. Top 9, 2 out - M. Conforto hit a solo home run (1) off R. Suarez. View the San Francisco Giants vs San Diego Padres game played on March 28, 2024. Box score, stats, odds, highlights ...Line 992 bus • 12 min. Take the line 992 bus from Broadway & Kettner Bl to San Diego Int'l Airport & Terminal 1 992. $2 - $5.Coast Starlight. Seattle. Portland. Sacramento. Los Angeles. 35 hours Daily Departure. A grand west coast train adventure, en route daily between Los Angeles and Seattle, the Coast Starlight train passes through Santa Barbara, the San Francisco Bay Area, Sacramento and Portland. Widely regarded as one of the most spectacular of all train … The total driving distance from San Francisco, CA to San Diego, CA is 501 miles or 806 kilometers. Your trip begins in San Francisco, California. It ends in San Diego, California. If you are planning a road trip, you might also want to calculate the total driving time from San Francisco, CA to San Diego, CA so you can see when you'll arrive at ... Expert recap and game analysis of the Arizona Diamondbacks vs. San Francisco Giants MLB game from April 19, 2024 on ESPN. ... SF -130. Over/Under: 7.5. Attendance: … Economy. 09/26/24 - 09/30/24. from. $ 159*. Viewed: 19 hours ago. From. San Diego (SAN) To. San Francisco (SFO) The distance between San Diego and San Francisco is 817 km, which takes a minimum of 10 hours 25 minutes. FlixBus has a large network, so you can travel onwards with us once you reach San Francisco. Tickets for this connection cost $116.99 on average, but you can book a trip for as little as $68.99. The lowest price for this connection is $68. ...Halfway Point Between San Diego, CA and San Francisco, CA. If you want to meet halfway between San Diego, CA and San Francisco, CA or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 35.561790 and -119.600899, or 35º 33' 42.444" N, 119º 36' 3.2364" W. This location is 250.65 miles …How far is it between San Francisco and San Diego. San Francisco is located in United States with (37.7749,-122.4194) coordinates and San Diego is located in United States with (32.7153,-117.1573) coordinates. The calculated flying distance from San Francisco to San Diego is equal to 458 miles which is equal to 738 km.. If you want to go by car, the …San Francisco. San Diego. The average train between San Francisco and San Diego takes 16h 30m and the fastest train takes 16h 27m. The train runs, on average, 6 times per week from San Francisco to San Diego. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.stay for about 1.5 hours. and leave at 7:02 pm. drive for about 23 minutes. 7:25 pm arrive in San Francisco. eat at Ike's Place. stay at Top of the Mark. day 2 driving ≈ 6 hours. find more stops.Select Frontier Airlines flight, departing Mon, Jun 10 from San Francisco to San Diego, returning Wed, Jun 19, priced at $66 found 12 hours ago. Tue, Oct 8 - Tue, Oct 22. SFO. San Francisco. SAN. San Diego. $68 Roundtrip, found 10 …The two airlines most popular with KAYAK users for flights from Oakland to San Diego are Alaska Airlines and Delta. With an average price for the route of $238 and an overall rating of 8.1, Alaska Airlines is the most popular choice. Delta is also a great choice for the route, with an average price of $362 and an overall rating of 8.0.How far is San Francisco from San Diego? Here's the quick answer if you are able to make this entire trip by car without stopping. Nonstop drive: 501 miles or 806 km. Driving time: 7 hours, 42 minutes. Realistically, you'll probably want to add a buffer for rest stops, gas, or food along the way.Finish your trip in San Diego for two nights! ... San Antonio, TX San Francisco, CA Seattle, WA Washington, DC Search by Map View Top 10 Destinations View all Destinations. Flash Sale 15+ Nights. Save $600. For a limited time only, save $600 per couple on rail vacations inclusive of 15 nights or more!Big Sur. ~ 146 miles from San Francisco & ~ 415 miles from San Diego. Another amazing stop on the San Francisco to San Diego drive or San Diego to San Francisco drive is Big Sur. This central coast is a magnificent escape for those travelers looking for a paradise.San Diego to San Francisco Flights. Flights from SAN to SFO are operated 81 times a week, with an average of 12 flights per day. Departure times vary between 06:15 - 22:14. The earliest flight departs at 06:15, the last flight departs at 22:14. However, this depends on the date you are flying so please check with the full flight schedule above ...To reach the midway point from San Francisco to San Diego, you would drive for about 4 hours, 3 minutes or roughly 251 miles from San Diego to the halfway stop. The exact coordinates of the midpoint are: 35° 29' 7" N. 119° 30' 57" W. The best place to meet based on recommendations from Trippy members is Bakersfield.Nonstop 1h 36m Frontier. Deal found 4/17 $51. Pick Dates. One of the most popular airlines traveling from San Francisco to San Diego is Frontier. Flights from Frontier traveling this route typically cost $247.66 RT. This price is typically 15% cheaper than other airlines that offer San Francisco to San Diego flights.There is no avoiding Los Angeles when driving from SF to SD. Even the coast is LA itself, from just south of Ventura all the way to the South Bay -- that coast is LA. SF to SD is at least a 9 hour drive. Report inappropriate content. BonnieandClyde86.Detailed flight information from San Francisco SFO to San Diego SAN. See all airline(s) with scheduled flights and weekly timetables up to 9 months ahead. Flightnumbers and complete route information. ... San Francisco , CA USA SAN. San Diego , CA Distance. 449 miles · (722 km) CHANGE DIRECTION. Flight time. 1 hour and 59 minutes. Mission Bay RV Resort (1 mention) Campland On The Bay (1 mention) Chula Vista RV Resort (1 mention) Admiral Baker Field Camp (1 mention) San Diego RV Resort-Sunland (1 mention) Of course, Trippy is the perfect place to ask questions because there's an entire community of travelers talking to each other and sharing tips and advice. Mar 31, 2023 · The top cities between San Francisco and San Diego are Los Angeles, Anaheim, Santa Monica, Carlsbad, San Jose, Temecula, Laguna Beach, Long Beach, Santa Clarita, and Malibu. Los Angeles is the most popular city on the route. It's 6 hours from San Francisco and 2 hours from San Diego. Show only these on map. Select Frontier Airlines flight, departing Mon, Jun 10 from San Francisco to San Diego, returning Wed, Jun 19, priced at $66 found 12 hours ago. Tue, Oct 8 - Tue, Oct 22. SFO. San Francisco. SAN. San Diego. $68 Roundtrip, found 10 …San Francisco to San Diego Flights. Flights from SFO to SAN are operated 87 times a week, with an average of 12 flights per day. Departure times vary between 05:40 - 22:15. The earliest flight departs at 05:40, the last flight departs at 22:15. However, this depends on the date you are flying so please check with the full flight schedule above ... San Francisco to San Diego bus times. Buses run once daily between San Francisco and San Diego. The service departs San Francisco at 22:00 at night, which arrives into San Diego at 08:55. All services run direct with no transfers required, and take on average 10h 55m. The schedules shown below are for the next available departures. See more reviews for this business. Top 10 Best Sf Supermarket in San Diego, CA - April 2024 - Yelp - SF Supermarket, 99 Ranch Market, Nijiya Market - San Diego, Mitsuwa Marketplace, Balboa International Market, Tokyo Central & Main - San Diego, H Mart - San Diego, Ocean Beach People's Food Co-op, Lucky Seafood.FlixBus has the lowest-fare tickets to San Diego. There are 1393 destinations in USA, and you can travel to many other countries, so no matter where you're traveling from, we can get you to San Diego. It couldn't be easier to book a bus ticket to San Diego with FlixBus. Tickets to San Diego start from only $7.99, subject to availability.May 16, 2022 · Recommended by Rebecca of Veggies Abroad – follow on Instagram. 10. Bixby Creek Bridge (the best views on this San Francisco to San Diego road trip) Iconic landmark: Bixby Creek Bridge on the California Coast drive. One of the most scenic stretches along the San Francisco to San Diego road trip is Big Sur. Fernando Tatis Jr.'s triple. Fernando Tatis Jr. triples to right field in the top of the 7th inning in a game vs. Rockies. The official website of the San Diego Padres with the most up-to-date information on scores, schedule, stats, tickets, and team news.The last time San Francisco hosted giant pandas was 1984-85, when two of the animals, Yun-Yun and Ying-Xin, were loaned to the zoo for close to three months, attracting four …The route was as follows:>. Arrive SF - Stayed for 3 nights, then made our way to Las Vegas Via Sacremento, Lake Tahoe, Yosemite. Stayed in Vegas for 4 nights, then drove to LA, which took 4-5 hours. Stayed in LA for 3 nights then made our back up to San Fran up the coast via Monterey. Then we stayed in SF for a few more nights.Cheap Flights from San Francisco to San Diego | United Airlines. United flights from San Francisco to San Diego from. $ 99. * 1 Passenger, Economy. Home. United flights. …The total flight duration from San Diego, CA to San Francisco, CA is 1 hour, 10 minutes. This is the average in-air flight time (wheels up to wheels down on the runway) based on actual flights taken over the past year, including routes like SAN to SFO. It covers the entire time on a typical commercial flight including take-off and landing.The best things to do in San Diego, California, include exploring Balboa Park, eating authentic Mexican food in Old Town, and relaxing on the shores of La Jolla.
Caltrain, with its partners Pacific Gas and Electric Company (PG&E) and Balfour Beatty, h... On the weekends of April 13-14 and April 20-21, Caltrain will be suspending morning and late-... San Francisco Giants fans can …. My texas health chart
San Francisco to San Diego bus times. Buses run once daily between San Francisco and San Diego. The service departs San Francisco at 22:00 at night, which arrives into San Diego at 08:55. All services run direct with no transfers required, and take on average 10h 55m. The schedules shown below are for the next available departures. The system will run from San Francisco to the Los Angeles basin in under three hours at speeds capable of over 200 miles per hour. The system will eventually extend to Sacramento and San Diego, totaling 800 miles with up to 24 stations. In addition, the Authority is working with regional partners to implement a state-wide rail modernization ...San Diego is a nice place to visit for snorkeling and scuba diving. However, San Francisco is not a scuba or snorkeling destination. San Diego has a few areas where visitors often go scuba diving or snorkeling. Popular snorkeling and diving spots include La Jolla Cove, Mission Bay, and Turtle Town. The total driving distance from San Francisco, CA to San Diego, CA is 501 miles or 806 kilometers. Your trip begins in San Francisco, California. It ends in San Diego, California. If you are planning a road trip, you might also want to calculate the total driving time from San Francisco, CA to San Diego, CA so you can see when you'll arrive at ... San Francisco and San Diego make great ends for the road trip. San Francisco is full of shops, restaurants, nightclubs, art galleries and coffeehouses. It is easy for a tourist to spend several days in the city. Pier 39 is one of the most popular tourist destinations in the world. It is also worthwhile to drive across the Golden Gate Bridge ...See more reviews for this business. Top 10 Best Sf Supermarket in San Diego, CA - April 2024 - Yelp - SF Supermarket, 99 Ranch Market, Nijiya Market - San Diego, Mitsuwa Marketplace, Balboa International Market, Tokyo Central & Main - San Diego, H Mart - San Diego, Ocean Beach People's Food Co-op, Lucky Seafood.Cheap Flights from SFO to SAN starting at $29 One Way, $58 Round Trip. Prices starting at $58 for return flights and $29 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply. Mon, May 13 - Tue, May 21.Jun 16, 2021 · San Diego and San Francisco, two of California's most popular coastal cities, are about 500 miles (806 kilometers) apart. You can make the trip by almost any common form of transportation, including train, bus, car, or plane. The fastest—and usually most affordable—way to get from San Diego to San Francisco is by flying. Cheap flights from San Francisco (SFO) to San Diego (SAN) Prices were available within the past 7 days and start at CA $67 for one-way flights and CA $176 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. Book one-way or return flights from San Francisco to San Diego with no change ...Scenic trip from San Francisco to San Diego. Question. I’m planning a trip for late January’24, from San Fran to San Diego. I have almost 2 days for this travel and really …San Diego (SAN) 07/11/24 - 07/18/24. from. $257* Updated: 4 hours ago. Round trip. I. Economy. See Latest Fare. keyboard_arrow_right *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking.San Diego is a nice place to visit for snorkeling and scuba diving. However, San Francisco is not a scuba or snorkeling destination. San Diego has a few areas where visitors often go scuba diving or snorkeling. Popular snorkeling and diving spots include La Jolla Cove, Mission Bay, and Turtle Town.Fastest route from San Diego to San Francisco. The quickest route between San Diego and San Francisco is the 502 mile drive north along Interstate 5, which takes about 8 hours. This inland route is, however, less scenic as a driving north on US Hwy 101 or directly along the California coast on Hwy 1. Driving on US 101 lengthens the drive by an ... San Francisco to San Diego bus times. Buses run once daily between San Francisco and San Diego. The service departs San Francisco at 22:00 at night, which arrives into San Diego at 08:55. All services run direct with no transfers required, and take on average 10h 55m. The schedules shown below are for the next available departures. Start from any of the 500+ Amtrak Stations across the United States. Upgrade to a sleeping accommodation onboard the train. Add extra nights in a favorite destination. Pick your own accommodation. Add additional sightseeing. Traveling by bus from San Francisco to San Diego usually takes around 15 hours and 14 minutes, but the fastest FlixBus US bus can make the trip in 10 hours and 35 minutes. … There are 6 daily trains from San Francisco to San Diego. Traveling by train from San Francisco to San Diego usually takes around 14 hours and 26 minutes, but the fastest Amtrak train can make the trip in 12 hours and 45 minutes. Distance. 458 mi (738 km) .